Anti-PAM/PAL antibody produced in goat, affinity isolated antibody, buffered aqueous solution

Biochem/physiol Actions

Peptidylglycine α-amidating monooxygenase (PAM) has a role in the biosynthesis of bioactive peptides. It is involved in C-terminal α-amidation, which influences the activity of regulatory peptides of the respiratory tract.

Features and Benefits

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General description

Peptidylglycine α-amidating monooxygenase (PAM) is expressed in endocrine cells and neurons. It consists of two enzyme activities- peptidyl-glycine α-hydroxylating monoxygenase (PHM) and peptidyl-α-hydroxyglycine amidating lyase (PAL). The PAM gene is localized on human chromosome 5q21.1.

Immunogen

Peptide with sequence C-DQEKEDDGSESEE from the C Terminus of the protein sequence according to NP_000910.2; NP_620121.1; NP_620176.1; NP_620177.1.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.